Osteo Strength

Size

90 capsules

Natural Product Number

80040928

Osteo Strength is Vitazan Professional’s highest-quality bone formula based on the form of calcium supplied and the spectrum of complementary nutrients included. Osteo Strength includes calcium and phosphorus derived from hydroxyapatite source. This source is the most bioavailable form of calcium, and has been shown to have superior effects on bone mineral density. In addition, this formula contains a wide array of complementary ingredients—including trace minerals, amino acids, as well as phytonutrients—that have been shown to exert additive beneficial effects on bone mineral density and calcium metabolism, when compared to supplementation of calcium alone.
Common conventional treatments for osteoporosis or bone loss include high-dose calcium and vitamin D supplementation, as well as bisphosphonate medications, antiresorptive medications that block the breakdown process of normal bone turnover. Currently, there is controversy of some of the side effects that have been associated with use of bisphosphonates, including osteonecrosis and possible increased risk of femoral fracture.
Use of combined nutrients for bone health is of high importance to ensure the maximal effectiveness as well as safety of calcium supplementation. High doses of calcium alone (~1 g or more) have been shown to increase long-term risk of cardiovascular events. It is crucial that calcium supplementation be accompanied by other nutrients that influence the proper metabolism and deposition of calcium such as vitamin D, vitamin K, and trace minerals. At full strength, Osteo Strength provides 900 mg calcium per day as well as a comprehensive array of supportive nutrients.
Safety: Women with a history of breast cancer should be cautious about using boron, due to possible estrogenic effects. Vitazan Professional’s Osteo Strength Boron‑Free formula is the most appropriate for such individuals.

SKU: 1854 Category:

Description

Suggested Use

Adults: Take 2 capsules one to three times daily with food or as directed by your health-care practitioner. If you are taking other medications, take this product a few hours before or after them.

Cautions and warnings:

Cautions and warnings: Consult a health-care practitioner prior to use if you are taking blood thinners; if you have gallstones or a bile duct obstruction; if you have stomach ulcers or excess stomach acid; if you are taking any prescription medications; if you have been diagnosed for or are at risk for a blood pressure disorder; if you have a liver disorder; if you have an iron deficiency; if you are following a low-protein diet; in the case of an estrogen-dependent cancer; or if you are taking antiplatelet medication. Discontinue use at least 2 weeks prior to surgery or dental procedures to prevent the risk of bleeding. Do not use if you are pregnant or breast-feeding. Discontinue use and consult a health-care practitioner if you develop symptoms of liver trouble such as yellowing of the skin/eyes (jaundice), stomach pain, dark urine, sweating, nausea, unusual tiredness, and/or loss of appetite. Rare, unpredictable cases of liver injury associated with green tea extract–containing products have been reported.

Ingredients

Each vegetable capsule contains:
Microcrystalline hydroxyapatite (freeze-dried MCHA)600 mg
Calcium (from calcium hydroxyapatite*)150 mg
Phosphorus (from calcium hydroxyapatite*)75 mg
Protein (from calcium hydroxyapatite*)150 mg
Magnesium (from magnesium biglycinate)24.16 mg
Zinc (from zinc monomethionine)1.55 mg
Manganese (from manganese [II] citrate)465 mcg
Copper (from copper [II] citrate)155 mcg
Boron (from boron citrate)560 mcg
Vitamin B₁ (thiamine hydrochloride)775 mcg
Vitamin K₂ (menaquinone‑4, menaquinone‑7)15.5 mcg
Field horsetail (Equisetum arvense aerial parts), 7% silica5 mg
Vitamin D₃ (cholecalciferol) (167 IU)4.17 mcg
Vitamin C (ʟ‑ascorbic acid)31 mg
Vitamin B₁₂ (methylcobalamin)25 mcg
Folate (from calcium ʟ‑5‑methyltetrahydrofolate)83.33 mcg
Lutein (oleoresin of Tagetes erecta [Asteraceae])333 mcg
Lycopene (pulp of ripe fruit of Lycopersicon esculentum [Solanaceae])833 mcg
ʟ‑Lysine (ʟ‑lysine monohydrochloride)50 mg
ʟ‑Proline50 mg
Glucosamine sulfate (crab/shrimp exoskeleton, stabilized with potassium chloride)42 mg
Turmeric (Curcuma longa) root extract, 95% curcuminoids, providing curcumin I, demethoxycurcumin, and bisdemethoxycurcumin3.33 mg
Grape (Vitis vinifera) seed extract, 95% proanthocyanidins10 mg
Green tea (Camellia sinensis) leaf extract, 75% EGCG7 mg
* From New Zealand cattle. Guaranteed free of bovine spongiform encephalopathy (BSE) and recombinant bovine growth hormone (rBGH).
Other ingredients: Microcrystalline cellulose, natural peppermint flavour, vegetable magnesium stearate, and silicon dioxide in a non‑GMO vegetable capsule composed of vegetable carbohydrate gum and purified water.

Individual Ingredients in Osteo Strenth Formula

DoseStudy DesignEffect

Calcium + Vitamin D: Benefit on BMD

500 mg calcium + 200 IU vitamin DDouble-blind controlled trial of calcium supplement versus placebo in 120 women over a 30-month treatment period.BMD of treatment group from 1.101 g/cm3 at baseline to 1.111 g/cm3 at 30 months; BMD of placebo group decreased from 1.102 g/cm3 at baseline to 1.098 g/cm3 at 30 months.
800 mg calcium citrateDouble blinded controlled trial of 63 postmenopausal women over 1–2 years.L2-L4 bone density: no change during calcium treatment (+1.03% after two years), but decline of −2.38% on placebo.

Magnesium: Benefit on Bone Turnover

250–750 mg magnesium hydroxide31 osteoporotic postmenopausal women and 23 controls receiving magnesium for two years.71% of magnesium group had 1–8% increases in trabecular BMD over 2 years. All treatment subjects showed increased BMD after 2 years; controls’ BMD decreased.

Vitamin K: Improves Calcium Metabolism and Deposition

45 mg menatetrenone (vitamin K₂)231 patients with Alzheimer’s receiving risedronate and calcium, with or without vitamin K × 1 year.BMD in the treatment group increased by 5.7% and 2.1% in the control group. Nonvertebral fractures occurred in 15 patients in the control group and 5 patients in the treatment group.

Boron: Benefit on Calcium Retention, Estrogenic Effects

3 mg boron167-day trial of 11 postmenopausal women given supplements of boron and/or magnesium.In subjects with low magnesium intake, supplemental boron decreased the percentage of dietary calcium lost in the urine.

Silica: Benefit on Bone Formation

3, 6, or 12 mg silicium as orthosilicic acid184 osteopenic women received 1g calcium +800mg vitaminD with or without orthosilicic acid × 1 yearThere was suggestion of additional benefit from silicon on markers of bone formation including collagen formation.

Zinc, Copper, Manganese: Benefit on BMD

15 mg zinc, 5 mg manganese, 2.5 mg copper, 1000 mg calcium59 postmenopausal women randomized to either 1000 mg calcium; 15 mg zinc, 5 mg manganese, and 2.5 mg copper; both of the above; or placebo over 2 years.All groups experienced loss of spinal BMD over intervention period compared to baseline, except for the calcium–zinc–copper–manganese group, which had an increase in BMD of 1.5%.

Folic Acid, Vitamin B₁₂, Vitamin B₆: Benefit on Bone Resorption and BMD

Low-dose vitamin B₆, B₁₂, folic acidOsteoporotic subjects (n = 47, 55–82 years) given a combination of folate, B₁₂, and B₆, or placebo.In hyperhomocysteinemic subjects, Bvitamins increased lumbar BMD and decreased markers of bone breakdown by 50%.

Vitamin C: Benefit on BMD

Mean daily dose was 745 mg.994 women from a community-based cohort of whom 277 women were regular vitamin C supplement users.After adjusting for age, body mass index (BMI), and total calcium intake, vitamin C users had BMD levels approximately 3% higher at the midshaft radius, femoral neck, and total hip.

ʟ‑Lysine: Benefit on BMD

Not specified40 subjects with osteoporosis given carbocalcitonin alone or with arginine-lysine-lactose.There was a greater increase in BMD in subjects treated with arginine-lysine-lactose, due to better intestinal calcium absorption mediated by lysine.

ʟ‑Proline: Component of Bone Matrix (Collagen)

Vitamins B, C, and 500 mg proline20 normal subjects and 40 women with osteopenia, given calcium and vitamin D with or without additional vitamin C, B, and proline × 1 year.Trabecular bone loss persisted in the osteopenic group receiving calcium +vitaminD only, but no further bone loss was detected in the group receiving additional proline. Osteoclastic activity was reduced.

Lycopene: Reduced Risk of Osteoporosis

Range: 1.76 to 7.35 mg/d.Cross-sectional study of 33 postmenopausal women of dietary lycopene.Higher serum lycopene was associated with a low NTx, a bone resorption marker.