|Natural Product Number|
Wormwood is used in traditional herbal medicine as a bitter tonic to stimulate appetite and as a vermifuge (to expel intestinal worms).
Grapefruit seed extract (GSE) contains bioactive flavonoids (e.g. hesperetin, resveratrol, and naringenin), and has been shown to possess antimicrobial effect against multiple species of bacteria and fungus. GSE has been shown to be effective in inhibiting the growth of an array of Gram-positive and Gram-negative bacterial organisms. GSE, in combination with geranium essential oil, has also demonstrated efficacy against methicillin-resistant Staphylococcus aureus (MRSA).
A laboratory study has shown that GSE possesses activity against Borrelia burgdorferi, the spirochete bacteria responsible for Lyme disease. Lower concentrations of GSE were found to cause disruption and herniation of the bacterial cell membrane, while at higher concentrations GSE “made the bacteria and cysts disappear completely, leaving only small uncharacteristic fragments.” Authors suggested that use of GSE alongside antibiotic therapy may increase the effectiveness of Lyme treatment, especially resistant forms, although these findings have yet to be replicated in humans.
Administration of GSE in animals has been shown to offset the development of stress- and ethanol-induced gastric ulcers. GSE had similar efficacy as anti-inflammatory analogs of PGE₂, and resulted in increased gastric blood flow, increased superoxide dismutase (SOD) activity, and decreased malonyldialdehyde (MDA), a marker of lipid peroxidation.
Controversy has arisen over the purported inclusion of synthetic preservatives, most notably benzethonium chloride, in many GSE extracts. Vitazan Professional’s Grapefruit Seed Extract has been thoroughly tested in our extensive lab facilities, and has been shown to be free of any synthetic preservatives.
Grapefruit juice is known to interact with a number of drugs by altering activity of the enzymes (CYP450) responsible for drug activation, breakdown, and elimination. Although the relevance of 100–400 mg GSE on drug interactions is unknown, patients on drug pharmacotherapy—especially blood thinners, beta blockers, certain antibiotics, and central nervous system drugs such as buspiron—should consult with a licensed health-care practitioner prior to use.
Adults (18+): Take 5 capsules twice daily or as directed by your health-care practitioner.
Duration of use: Consult a health-care practitioner for use beyond 1 month.
Cautions and warnings:
Cautions and warnings: Do not exceed recommended dose. Consult a health-care practitioner prior to use if you are taking immunosuppressants; if you have an autoimmune disorder; if you have a progressive systemic disease such as tuberculosis, leucosis, collagenosis, multiple sclerosis, AIDS and/or HIV infection; if you have liver disorders, biliary disorders, and/or seizure disorders; or if you are taking other medications. Consult a health-care practitioner if symptoms persist or worsen.
Contraindications: Do not use if you are pregnant or breast-feeding, if you have been diagnosed with a gastric or duodenal ulcer, or if you have high stomach acidity.
Known adverse reactions: Hypersensitivity has been known to occur; discontinue use if signs such as allergy appears.
|Each vegetable capsule contains:|
|Echinacea (Echinacea angustifolia) root||161 mg|
|Wormwood (Artemisia absinthium) aerial parts||161 mg|
|Grapefruit seed extract||84 mg|
|Other ingredients: Silicon dioxide and vegetable magnesium stearate in a non‑GMO vegetable capsule composed of vegetable carbohydrate gum and purified water.|