|Natural Product Number|
Ginger (Zingiber officinale) has traditionally been used for its tonifying effects on the digestive system as well as for conditions related to pain and inflammation. Ginger has been used in China for thousands of years for headaches, nausea, and colds, while in the Mediterranean region, ginger has been used for the treatment of muscular pain and arthritis.
Ginger contains phenolic compounds called gingerols, of which 6‑gingerol is thought to be the most bioactive. For instance, with respect to nausea, 6‑gingerol has been shown to exert antiemetic activity by inhibiting neurokinin‑1, serotonin, and dopamine receptors in preclinical models. 6‑Gingerol has also demonstrated several important anticancer effects including antiproliferative, antitumour, anti-invasive, and anti-inflammatory activities. 6‑Gingerol and other active constituents of ginger have been demonstrated in one simulation study to cross the blood-brain barrier via passive diffusion, thereby supporting its possible effects on the central nervous system.
Ginger has been the subject of a large amount of scientific research. Several meta-analyses have evaluated the use of ginger for support in conditions including nausea of various kinds, menstrual pain (dysmenorrhea), osteoarthritis, and blood sugar control.
- Kalantari, K., et al. “A review of the biomedical applications of zerumbone and the techniques for its extraction from ginger rhizomes.” Molecules, Vol. 22, No. 10 (2017). pii: E1645.
- de Lima, R.M.T., et al. “Protective and therapeutic potential of ginger (Zingiber officinale) extract and ‑gingerol in cancer: A comprehensive review.” Phytotherapy Research, Vol. 32, No. 10 (2018): 1885–1907.
- Konmun, J., et al. “A phase II randomized double-blind placebo-controlled study of 6‑gingerol as an anti-emetic in solid tumor patients receiving moderately to highly emetogenic chemotherapy.” Medical Oncology, Vol. 34, No. 4 (2017): 69.
- Simon, A., et al. “Blood-brain barrier permeability study of ginger constituents.” Journal of pharmaceutical and biomedical analysis. (2019): 1977 [Epub ahead of print]
- Bartels, E.M., et al. “Efficacy and safety of ginger in osteoarthritis patients: A meta-analysis of randomized placebo-controlled trials.” Osteoarthritis and Cartilage, Vol. 23, No. 1 (2015): 13–21.
- Daily, J.W., et al. “Efficacy of ginger for alleviating the symptoms of primary dysmenorrhea: A systematic review and meta-analysis of randomized clinical trials.” Pain Medicine, Vol. 16, No. 12 (2015): 2243–2255.
- Huang, F.Y., et al. “Dietary ginger as a traditional therapy for blood sugar control in patients with type 2 diabetes mellitus: A systematic review and meta-analysis.” Medicine, Vol. 98, No. 13 (2019): e15054.
- Sridharan, K., and G. Sivaramakrishnan. “Interventions for treating nausea and vomiting in pregnancy: A network meta-analysis and trial sequential analysis of randomized clinical trials.” Expert Review of Clinical Pharmacology, Vol. 11, No. 11 (2018): 1143–1150.
- Tóth, B., et al. “Ginger (Zingiber officinale): An alternative for the prevention of postoperative nausea and vomiting. A meta-analysis.” Phytomedicine, Vol. 50 (2018): 8–18.
Adults: Take 1 capsule daily or as directed by your health-care practitioner. For nausea: Take a single dose 30 minutes before travel.
Cautions and warnings:
Cautions and warnings: Consult a health-care practitioner if symptoms persist or worsen.
|Each vegetarian capsule contains:|
|Ginger (Zingiber officinale)||100 mg|
|Ginger (Zingiber officinale) 20:1 extract, 10% gingerols||6.25 mcg|
|Non-medicinal ingredients: Vegetable magnesium stearate and silicon dioxide in a non‑GMO vegetable capsule composed of vegetable carbohydrate gum and purified water.|
|Contains no: Gluten, soy, wheat, corn, eggs, dairy, yeast, citrus, preservatives, artificial flavor or colour, starch, or sugar.|